Nature Communications (Jan 2016)

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

  • Katri Korpela,
  • Anne Salonen,
  • Lauri J. Virta,
  • Riina A. Kekkonen,
  • Kristoffer Forslund,
  • Peer Bork,
  • Willem M. de Vos

DOI
https://doi.org/10.1038/ncomms10410
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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The impact of antibiotics on the microbiome and health of children is poorly understood. Here, Korpela et al. study the gut microbiome of 142 children and show that the use of macrolides, but not penicillins, is associated with long-lasting shifts in microbiota composition and increased risk of asthma and overweight.