Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites

Abstract

Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).