Communications Biology (Sep 2022)
Choice of Voxel-based Morphometry processing pipeline drives variability in the location of neuroanatomical brain markers
- Xinqi Zhou,
- Renjing Wu,
- Yixu Zeng,
- Ziyu Qi,
- Stefania Ferraro,
- Lei Xu,
- Xiaoxiao Zheng,
- Jialin Li,
- Meina Fu,
- Shuxia Yao,
- Keith M. Kendrick,
- Benjamin Becker
Affiliations
- Xinqi Zhou
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Renjing Wu
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Yixu Zeng
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Ziyu Qi
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Stefania Ferraro
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Lei Xu
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Xiaoxiao Zheng
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Jialin Li
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Meina Fu
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Shuxia Yao
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Keith M. Kendrick
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- Benjamin Becker
- The Center of Psychosomatic Medicine, Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, MOE Key Laboratory for Neuroinformation, High-Field Magnetic Resonance Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China
- DOI
- https://doi.org/10.1038/s42003-022-03880-1
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 12
Abstract
Four common processing pipelines tested on two Voxel-based Morphometry (VBM) datasets yield considerable variations in results, raising issues on the interpretability and robustness of VBM results.
