mSystems (Aug 2021)

Comprehensive Cultivation of the Swine Gut Microbiome Reveals High Bacterial Diversity and Guides Bacterial Isolation in Pigs

  • Xiaofan Wang,
  • Samantha Howe,
  • Xiaoyuan Wei,
  • Feilong Deng,
  • Tsungcheng Tsai,
  • Jianmin Chai,
  • Yingping Xiao,
  • Hua Yang,
  • Charles V. Maxwell,
  • Ying Li,
  • Jiangchao Zhao

DOI
https://doi.org/10.1128/mSystems.00477-21
Journal volume & issue
Vol. 6, no. 4

Abstract

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The swine gut microbiome has been the focus of many investigations due to the fact that pigs serve as both an excellent biomedical model for human diseases and an important protein source. Substantial progress has been made in swine gut microbiome studies using next-generation sequencing-based culture-independent approaches, but little is known about the culturability of the swine gut microbiota.