Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats

Vinícius Elias de Moura Oliveira; Michael Lukas; Hannah Nora Wolf; Elisa Durante; Alexandra Lorenz; Anna-Lena Mayer; Anna Bludau; Oliver J. Bosch; Valery Grinevich; Veronica Egger; Trynke R. de Jong; Inga D. Neumann

doi:10.1038/s41467-021-23064-5

Nature Communications (May 2021)

Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats

Vinícius Elias de Moura Oliveira,
Michael Lukas,
Hannah Nora Wolf,
Elisa Durante,
Alexandra Lorenz,
Anna-Lena Mayer,
Anna Bludau,
Oliver J. Bosch,
Valery Grinevich,
Veronica Egger,
Trynke R. de Jong,
Inga D. Neumann

Affiliations

Vinícius Elias de Moura Oliveira: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Michael Lukas: Department of Neurobiology and Animal Physiology, Neurophysiology, University of Regensburg
Hannah Nora Wolf: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Elisa Durante: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Alexandra Lorenz: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Anna-Lena Mayer: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Anna Bludau: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Oliver J. Bosch: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Valery Grinevich: Department of Neuropeptide Research in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg
Veronica Egger: Department of Neurobiology and Animal Physiology, Neurophysiology, University of Regensburg
Trynke R. de Jong: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg
Inga D. Neumann: Department of Neurobiology and Animal Physiology, Behavioural and Molecular Neurobiology, University of Regensburg

DOI: https://doi.org/10.1038/s41467-021-23064-5
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 15

Abstract

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Aggression in females is understudied in model organisms. Here, the authors establish a model of enhanced aggression in virgin female rats and show that oxytocin and vasopressin systems differentially modulate aggression in distinct neuronal populations of the lateral septum of female rats.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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