Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator

I. Cody MacDonald; Travis R. Seamons; Jonathan C. Emmons; Shwan B. Javdan; Tara L. Deans

doi:10.1038/s41467-021-24434-9

Nature Communications (Jul 2021)

Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator

I. Cody MacDonald,
Travis R. Seamons,
Jonathan C. Emmons,
Shwan B. Javdan,
Tara L. Deans

Affiliations

I. Cody MacDonald: Department of Biomedical Engineering, University of Utah
Travis R. Seamons: Department of Biomedical Engineering, University of Utah
Jonathan C. Emmons: Department of Biomedical Engineering, University of Utah
Shwan B. Javdan: Department of Biomedical Engineering, University of Utah
Tara L. Deans: Department of Biomedical Engineering, University of Utah

DOI: https://doi.org/10.1038/s41467-021-24434-9
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 10

Abstract

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Expanded toolkits for prokaryotic synthetic biology can enhance the dynamic range of gene expression. Here the authors move the eukaryotic transcription factor QF into E. coli and integrate it into genetic devices.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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