Transplantology (Mar 2022)

Are CMV and SARS-CoV-2 Infections Mutual Risk Factors in Kidney Transplant Recipients?

  • Julia Swist,
  • Mateusz Krotofil,
  • Oktawia Mazanowska,
  • Magdalena Krajewska,
  • Dorota Kamińska

DOI
https://doi.org/10.3390/transplantology3010010
Journal volume & issue
Vol. 3, no. 1
pp. 103 – 108

Abstract

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Throughout the years, much progress has been made in the field of renal transplantation; however, along with new developments, new problems have arisen. While transplantation is the optimal choice in patients suffering from end-stage renal disease, it is always connected to certain commonly associated risks, in particular those caused by opportunistic infections. One such risk includes the reactivation of cytomegalovirus (CMV), an issue commonly affecting all kinds of transplant recipients. Similarly, with the rise of the ever-evolving global SARS-CoV-2 pandemic, patients must be constantly monitored for any respiratory symptoms, and observed closely under the care of their attending physician. Treating these patients has become extremely difficult due to limitations caused by COVID-19 protocols (for instance, the reduction of immunosuppression dosages and the avoidance of lymphocyte-depleting induction therapy) and the lack of knowledge surrounding this relatively new and worsening risk factor. In order to give patients optimal care, these arising problems need to be studied and addressed.

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