Antimicrobial Treatment Strategies for <i>Steno</i><i>trophomonas maltophilia</i>: A Focus on Novel Therapies

Abstract

Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activity for Stenotrophomonas. Accordingly, novel treatment strategies for Stenotrophomonas are desperately needed. We conducted a systemic literature review and offer recommendations based on current evidence for a treatment strategy of Stenotrophomonas infection.

Keywords

• <i>Stenotrophomonas</i>
• <i>Stenotrophomonas maltophilia</i>
• treatment
• cefiderocol
• avibactam
• aztreonam