mBio
(Jun 2021)
Genome Scale Analysis Reveals IscR Directly and Indirectly Regulates Virulence Factor Genes in Pathogenic
<i>Yersinia</i>
David Balderas,
Erin Mettert,
Hanh N. Lam,
Rajdeep Banerjee,
Tomas Gverzdys,
Pablo Alvarez,
Geetha Saarunya,
Natasha Tanner,
Adam Zoubedi,
Yahan Wei,
Patricia J. Kiley,
Victoria Auerbuch
Affiliations
David Balderas
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Erin Mettert
Department of Biomolecular Chemistry, University of Wisconsin—Madison, Madison, Wisconsin, USA
Hanh N. Lam
ORCiD
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Rajdeep Banerjee
Department of Biomolecular Chemistry, University of Wisconsin—Madison, Madison, Wisconsin, USA
Tomas Gverzdys
Department of Biomolecular Chemistry, University of Wisconsin—Madison, Madison, Wisconsin, USA
Pablo Alvarez
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Geetha Saarunya
Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA
Natasha Tanner
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Adam Zoubedi
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Yahan Wei
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
Patricia J. Kiley
Department of Biomolecular Chemistry, University of Wisconsin—Madison, Madison, Wisconsin, USA
Victoria Auerbuch
ORCiD
Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, USA
DOI
https://doi.org/10.1128/mBio.00633-21
Journal volume & issue
Vol. 12,
no. 3
Abstract
Read online
How bacteria adapt to the changing environment within the host is critical for their ability to survive and cause disease. For example, the mammalian host severely restricts iron availability to limit bacterial growth, referred to as nutritional immunity.
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