Study of Changing Trend in the Clinical Distribution of Candida Species in Various Clinical Samples at Tertiary Care Hospital, Ahmedabad, Gujarat

Abstract

Introduction: The incidence of fungal infections has increased significantly, contributing to morbidity and mortality. Candida albicans remains the most common species causing human infections but recent epidemiological data reveal shift from C. albicans to non albicans Candida species. The aim of our study is to detect the clinical distribution of Candida species in a tertiary hospital. Materials and Methods: Study of identification of Candida species was carried out at tertiary care hospital of Ahmedabad from 1st January 2016 to 30th June 2016.Total 102 candida isolates were identified from various clinical samples.. Identification of Candida species was done by standard techniques which include growth on Sabouraud dextrose agar and Chrom agar, Sabouraud dextrose broth, Germ tube test, slide culture on Cornmeal agar ,urease test and Carbohydrate utilization pattern by sugar assimilation test. Results: Out of 102 Candida isolates collected 58% were from males and 42% from females. The distribution of the clinical samples was urine 51.96%, exudates 14.70%, respiratory 13.72% and blood 19.60%. In this study most frequently isolated Candida species was C. tropicalis 43 (42.15%) followed by C. albicans 37 (36.27%), C. guillermondii 14 (13.72%), and C. parapsilosis 4 (3.92%). C. kruzei 4 (3.92%). C.tropicalis was mainly isolated from urine samples. Conclusions: The present study shows increased incidence of non albicans Candida as compared to Candida albicans.

Keywords

• Candida
• Species
• infection
• chrom agar
• Clinical