Changes in Arrangement of Chondrons in Radial Zone of Ageing Male Human Articular Cartilage

Abstract

Background: To study the variation in arrangement of chondrons in radial zone of male human articular cartilage. Methods: Forty samples of articular cartilage from male dead bodies ageing between 21 – 60 years were collected and divided into four groups. After tissue processing and cutting, H&E and special staining with Masson’s Trichrome was done and arrangement of chondrons was noted. Results: With advancing age the arrangements of chondrons in radial zone of group A, B and C was in short columns while in group D, the arrangement was disturbed. The chondrons were observed in pairs and clusters. Conclusion: In ageing articular cartilage the arrangements of chondrons in radial zone of articular cartilage is altered leading to osteoarthritis that makes it focus of intense study for preventive measures and treatment.

Keywords

• Articular cartilage
• Chondrons
• Radial zone
• Osteoarthritis