JCO Global Oncology (May 2023)

Clinical Outcomes and Prognostic Factors of Patients With Early Malignant Melanoma in One Latin American Country: Results of the Epidemiological Registry of Malignant Melanoma in Colombia Study

  • Aylen Vanessa Ospina Serrano,
  • Fernando Contreras,
  • Iván Triana,
  • Guillermo Sánchez-Vanegas,
  • Juan David Ortíz,
  • Pedro Ramos,
  • Claudia Vargas,
  • Natalia Arango,
  • Henry Idrobo,
  • Isabel Munévar,
  • Andrés Yepes,
  • William Mantilla,
  • Paola Jiménez,
  • Giovanna Rivas,
  • Mauricio Lema,
  • Carmen Alcalá,
  • Diego Gómez,
  • Matilde Chinchia,
  • Angela Barrero

DOI
https://doi.org/10.1200/GO.22.00377
Journal volume & issue
no. 9

Abstract

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To describe the population with early malignant melanoma, we performed a cohort study on the basis of the Epidemiological Registry of Malignant Melanoma in Colombia-Asociacion Colombiana de Hematologia y Oncologia. From January 2011 until December 2021, 759 patients were included; the average age was 66 years, 57% were women, acral lentiginous histology was found in 27.8% of patients, and the median follow-up was 36.5 months. The prognostic factors for overall survival in our population are Eastern Cooperative Oncology Group 3-4 (hazard ratio [HR], 13.8), stage III (HR, 5.07), received radiotherapy (HR, 3.38), ulceration on histology (HR, 2.68), chronic sun exposure (HR, 2.3), low income (HR, 2.04), previous local surgery (HR, 0.27), and have received adjuvant treatment (HR, 0.41).