A CASE REPORT OF MORVAN SYNDROME, THE UNIQUE CLINICAL PATTERN OF A RARE DISEASE

Abstract

Morvan syndrome is a rare autoimmune disorder mediated by antibodies against voltage-gated potassium channels (VGKC) and characterized by the involvement of both the peripheral and central nervous system. We report a case of Morvan syndrome. The patient presented with peripheral nerve hyperexcitability, dysautonomia and neuropsychiatric symptoms. The diagnosis was based on the unique clinical presentation that was highly suggestive of Morvan syndrome and confirmed by positive VGKC antibodies. In this paper we try to highlight the importance of clinical skills in the diagnosis and decision-making concerning the treatment process.

Keywords

• morvan syndrome
• peripheral nerve hyperexcitability
• dysautonomia
• encephalopathy
• vgkc