Structural Elucidation and NMR Spectral Assignments of Two C19-Diterpenoid Alkaloids

YIN Tian-peng; CHEN Yang; LUO Ping; CAL Le; DING Zhong-tao

doi:10.11938/cjmr20172583

Chinese Journal of Magnetic Resonance (Mar 2018)

Structural Elucidation and NMR Spectral Assignments of Two C19-Diterpenoid Alkaloids

YIN Tian-peng,
CHEN Yang,
LUO Ping,
CAL Le,
DING Zhong-tao

Affiliations

YIN Tian-peng: 1. Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhuhai Campus, Zhuhai 519041, China; 2. Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
CHEN Yang: Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhuhai Campus, Zhuhai 519041, China
LUO Ping: Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
CAL Le: Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
DING Zhong-tao: Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China

DOI: https://doi.org/10.11938/cjmr20172583
Journal volume & issue: Vol. 35, no. 1
pp. 90 – 97

Abstract

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Two C19-diterpenoid alkaloids, homochasmanine (compound 1) and 14-debenzoylfranchetine (compound 2), were isolated from the roots of Aconitum handelianum. Their structures were elucidated by one-dimensional and two-dimensional nuclear magnetic resonance (NMR) techniques, including 1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC and NOESY. The 1H and 13C NMR signals of the compounds were completely assigned.

Published in Chinese Journal of Magnetic Resonance

ISSN: 1000-4556 (Print)
Publisher: Science Press
Country of publisher: China
LCC subjects: Science: Physics: Electricity and magnetism
Website: http://121.43.60.238/bpxzz/EN/1000-4556/home.shtml

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