Viruses (Jul 2020)

<i>Pseudomonas</i> Phage PaBG—A Jumbo Member of an Old Parasite Family

  • Peter Evseev,
  • Nina Sykilinda,
  • Anna Gorshkova,
  • Lidia Kurochkina,
  • Rustam Ziganshin,
  • Valentin Drucker,
  • Konstantin Miroshnikov

DOI
https://doi.org/10.3390/v12070721
Journal volume & issue
Vol. 12, no. 7
p. 721

Abstract

Read online

Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages.

Keywords