Hereditary Spherocytosis in Pregnancy-A Case Report

Abstract

Hereditary Spherocytosis (HS) is the most common inherited red cell membrane disorder included under intracorpuscular defect. The HS has both autosomal dominant and autosomal recessive inheritance. The disease may be mild, moderate or severe and requires a multidisciplinary approach for its management during pregnancy. Hereby, authors present a case of a 30-year-old female G2P1L1 at 34 weeks+4 days presented with anaemia not responding to iron therapy since first trimester. Peripheral blood smear revealed red blood cell’s were normocytic and normochromic. Spherocytes were seen with mild polychromatophilia and diagnosed as a case of HS and its management was done with haematological support.

Keywords

• anaemia
• haemolysis
• multidisciplinary approach
• splenectomy