Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function

Min Jung; Michelle Dourado; James Maksymetz; Amanda Jacobson; Benjamin I. Laufer; Miriam Baca; Oded Foreman; David H. Hackos; Lorena Riol-Blanco; Joshua S. Kaminker

doi:10.1038/s41467-023-36014-0

Nature Communications (Jan 2023)

Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function

Min Jung,
Michelle Dourado,
James Maksymetz,
Amanda Jacobson,
Benjamin I. Laufer,
Miriam Baca,
Oded Foreman,
David H. Hackos,
Lorena Riol-Blanco,
Joshua S. Kaminker

Affiliations

Min Jung: Department of OMNI Bioinformatics, Genentech, Inc.
Michelle Dourado: Department of Neuroscience, Genentech, Inc.
James Maksymetz: Department of Neuroscience, Genentech, Inc.
Amanda Jacobson: Department of Immunology Discovery, Genentech, Inc.
Benjamin I. Laufer: Department of OMNI Bioinformatics, Genentech, Inc.
Miriam Baca: Department of Pathology, Genentech, Inc.
Oded Foreman: Department of Pathology, Genentech, Inc.
David H. Hackos: Department of Neuroscience, Genentech, Inc.
Lorena Riol-Blanco: Department of Immunology Discovery, Genentech, Inc.
Joshua S. Kaminker: Department of OMNI Bioinformatics, Genentech, Inc.

DOI: https://doi.org/10.1038/s41467-023-36014-0
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 15

Abstract

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Sensory neurons are critical for maintaining tissue homeostasis. Here, the authors generated a single-nuclei cross-species atlas of the dorsal root ganglia, revealing conserved programs for sensory function that could inform therapeutic hypotheses.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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