Ultrasound assisted synthesis of 1-amino-3-ferrocenyl-3-oxoprop-1-enes

Abstract

A clean and efficient, mediated in water and assisted by ultrasound method for the synthesis of a series of N-substituted 1-amino-3-ferrocenyl-3-oxoprop-1-enes starting from acetyl ferrocene was developed. Our approach offers shortening of the reaction time under the mild reaction conditions and easy work up procedure.

Keywords

• Enaminones
• Michael addition
• Nucleophilic substitution
• Crystal structure