Annals of Microbiology (May 2024)

Research progress on the polysaccharide extraction and antibacterial activity

  • Lihui Liang,
  • Qihang Su,
  • Yu Ma,
  • Shuzhen Zhao,
  • Huanjie Zhang,
  • Xiaofeng Gao

DOI
https://doi.org/10.1186/s13213-024-01762-x
Journal volume & issue
Vol. 74, no. 1
pp. 1 – 13

Abstract

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Abstract Background Over time, the amount of germs resistant to antibacterial medications has been steadily rising because of their prolonged and indiscriminate use. The increase in drug resistance significantly threatens to human health and has become a globally recognized issue of concern. Therefore, identifying new antibacterial drugs is urgently needed. Forward Polysaccharides are natural macromolecular substances that exist in plants, microorganisms, and animals, They have an immense amount of use in the food and medical industries. Polysaccharides can be categorized as plant, animal, or microbial based on the sources of the polysaccharides. Conclusion Polysaccharides are natural compounds with antibacterial properties that exerts antibacterial activity by disrupting bacterial cell walls and cell membranes. They show potential as candidates for the creation and application of novel antibiotics. This article reviews the classification of polysaccharides, their isolation and purification, mechanisms of action, and antibacterial activity. The primary objective of this study is to lay down an empirical groundwork for examining the antibacterial properties of polysaccharides.

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