Toxins (Feb 2023)

Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19

  • Isadora Oliveira,
  • Isabela Ferreira,
  • Beatriz Jacob,
  • Kiara Cardenas,
  • Felipe Cerni,
  • Djane Baia-da-Silva,
  • Eliane Arantes,
  • Wuelton Monteiro,
  • Manuela Pucca

DOI
https://doi.org/10.3390/toxins15020159
Journal volume & issue
Vol. 15, no. 2
p. 159

Abstract

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Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an increase in in-depth studies on antiviral agents, and since, to date, there has been no completely effective drug against the global disease. This review explores the crosstalk of animal toxins and COVID-19, aiming to map potential therapeutic agents derived from venoms (e.g., bees, snakes, scorpions, etc.) targeting COVID-19.

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