Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments

• Hans Minderman,
• Maulasri Bhatta,
• Gautam N Shenoy,
• Jenni L Loyall,
• Brian D Gray,
• Meghana Bapardekar,
• Alexis Conway,
• Raymond J Kelleher Jr,
• Beatriz M Carreno,
• Gerald Linette,
• Leonard D Shultz,
• Sathy V Balu-Iyer,
• Koon Yan Pak,
• Richard B Bankert

Affiliations

Hans Minderman

Flow & Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA

Maulasri Bhatta

Immune Modulatory Therapies LLC, Eden, New York, USA

Gautam N Shenoy

Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA

Jenni L Loyall

Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA

Brian D Gray

Molecular Targeting Technologies Inc, West Chester, Pennsylvania, USA

Meghana Bapardekar

Flow & Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA

Alexis Conway

Flow & Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA

Raymond J Kelleher Jr

Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA

Beatriz M Carreno

Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Gerald Linette

Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Leonard D Shultz

Jackson Laboratory, Bar Harbor, Maine, USA

Sathy V Balu-Iyer

Department of Pharmaceutical Sciences, University at Buffalo–The State University of New York, Buffalo, New York, USA

Koon Yan Pak

Molecular Targeting Technologies Inc, West Chester, Pennsylvania, USA

Richard B Bankert

Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA