Predictive value of serum MED1 and PGC-1α for bronchopulmonary dysplasia in preterm infants

Mengzhao Li; Wenqiang Sun; Changchang Fu; Shuyang Xu; Chengzhu Wang; Huijuan Chen; Xueping Zhu

doi:10.1186/s12890-024-03145-z

BMC Pulmonary Medicine (Jul 2024)

Predictive value of serum MED1 and PGC-1α for bronchopulmonary dysplasia in preterm infants

Mengzhao Li,
Wenqiang Sun,
Changchang Fu,
Shuyang Xu,
Chengzhu Wang,
Huijuan Chen,
Xueping Zhu

Affiliations

Mengzhao Li: Department of Neonatology, Children’s Hospital of Soochow University
Wenqiang Sun: Department of Neonatology, Children’s Hospital of Soochow University
Changchang Fu: Department of Neonatology, Children’s Hospital of Soochow University
Shuyang Xu: Department of Neonatology, Children’s Hospital of Soochow University
Chengzhu Wang: Department of Neonatology, Children’s Hospital of Soochow University
Huijuan Chen: Department of Neonatology, Children’s Hospital of Soochow University
Xueping Zhu: Department of Neonatology, Children’s Hospital of Soochow University

DOI: https://doi.org/10.1186/s12890-024-03145-z
Journal volume & issue: Vol. 24, no. 1
pp. 1 – 10

Abstract

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Abstract Objective This study aimed to predict the bronchopulmonary dysplasia (BPD) in preterm infants with a gestational age(GA) 7 d, and time to reach total enteral nutrition. Our predictive model had a high predictive accuracy(C statistics of 0.989) . Conclusion MED1and PGC-1α could potentially serve as valuable biomarkers, combined with clinical factors, to aid clinicians in the early diagnosis of BPD.

Published in BMC Pulmonary Medicine

ISSN: 1471-2466 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://bmcpulmmed.biomedcentral.com

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Abstract

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