Антибиотики и Химиотерапия (May 2020)
Antibacterial and Antimycotic Properties of Granular Carbon Sorbents Modified With Lactic Acid Oligomers
Abstract
Results of the microbiological bench testing of antibacterial and antimycotic activity of the carbon sorbents modified with lactic acid oligomers are presented. It was found that the studied microorganisms - Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus agalactiae, Enterococcus faecalis, Pseudomonas aeruginosa, Streptococcus pyogenes, Klebsiella pneumonia, and Escherichia coli - are resistant to the majority of antimicrobial preparations that are widely used nowadays in clinical practice for treatment of bacterial and mycotic infectious diseases. Antimycotic effect of the modified sorbents toward yeast-like fungi Candida albicans was revealed. It was established for the first time that the modified sorbents have pronounced antimicrobial properties toward associative bacterial-fungal culture S.aureus + C.albicans, especially the carbon sorbent that was modified with a 50% lactic acid solution with subsequent polycondensation.