Pd(OAc)2-catalyzed dehydrogenative C–H activation: An expedient synthesis of uracil-annulated β-carbolinones

Abstract

An intramolecular dehydrogenative C–H activation enabled an efficient synthesis of an uracil-annulated β-carbolinone ring system. The reaction is simple, efficient and high yielding (85–92%).

Keywords

• β-carbolinones
• cyclization
• dehydrogenative C–H activation
• Pd(OAc)2
• uracil