Fission yeast Dis1 is an unconventional TOG/XMAP215 that induces microtubule catastrophe to drive chromosome pulling

Yuichi Murase; Masahiko Yamagishi; Naoyuki Okada; Mika Toya; Junichiro Yajima; Takahiro Hamada; Masamitsu Sato

doi:10.1038/s42003-022-04271-2

Communications Biology (Nov 2022)

Fission yeast Dis1 is an unconventional TOG/XMAP215 that induces microtubule catastrophe to drive chromosome pulling

Yuichi Murase,
Masahiko Yamagishi,
Naoyuki Okada,
Mika Toya,
Junichiro Yajima,
Takahiro Hamada,
Masamitsu Sato

Affiliations

Yuichi Murase: Laboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University
Masahiko Yamagishi: Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
Naoyuki Okada: Laboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University
Mika Toya: Laboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University
Junichiro Yajima: Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
Takahiro Hamada: Department of Bioscience, Faculty of Life Science, Okayama University of Science
Masamitsu Sato: Laboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University

DOI: https://doi.org/10.1038/s42003-022-04271-2
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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Members of the conserved TOG/XMAP215 family possess microtubule polymerase activities; however, Dis1 in fission yeast is shown to promote microtubule catastrophe.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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