Frontiers in Neurology (Mar 2022)

Postural Sway in Parkinson's Disease and Multiple Sclerosis Patients During Tasks With Different Complexity

  • Elke Warmerdam,
  • Elke Warmerdam,
  • Maike Schumacher,
  • Thorben Beyer,
  • Patrik Theodor Nerdal,
  • Linda Schebesta,
  • Klarissa H. Stürner,
  • Kirsten E. Zeuner,
  • Clint Hansen,
  • Walter Maetzler

DOI
https://doi.org/10.3389/fneur.2022.857406
Journal volume & issue
Vol. 13

Abstract

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Neurological diseases are associated with static postural instability. Differences in postural sway between neurological diseases could include “conceptual” information about how certain symptoms affect static postural stability. This information might have the potential to become a helpful aid during the process of finding the most appropriate treatment and training program. Therefore, this study investigated static postural sway performance of Parkinson's disease (PD) and multiple sclerosis (MS) patients, as well as of a cohort of healthy adults. Three increasingly difficult static postural tasks were performed, in order to determine whether the postural strategies of the two disease groups differ in response to the increased complexity of the balance task. Participants had to perform three stance tasks (side-by-side, semi-tandem and tandem stance) and maintain these positions for 10 s. Seven static sway parameters were extracted from an inertial measurement unit that participants wore on the lower back. Data of 47 healthy adults, 14 PD patients and 8 MS patients were analyzed. Both healthy adults and MS patients showed a substantial increase in several static sway parameters with increasingly complex stance tasks, whereas PD patients did not. In the MS patients, the observed substantial change was driven by large increases from semi-tandem and tandem stance. This study revealed differences in static sway adaptations between PD and MS patients to increasingly complex stance tasks. Therefore, PD and MS patients might require different training programs to improve their static postural stability. Moreover, this study indicates, at least indirectly, that rigidity/bradykinesia and spasticity lead to different adaptive processes in static sway.

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