Lopinavir/ritonavir did not shorten the duration of SARS CoV-2 shedding in patients with mild pneumonia in Taiwan

Chien-Yu Cheng; Yu-Lin Lee; Cheng-Pin Chen; Yi-Chun Lin; Chun-Eng Liu; Chia-Hung Liao; Shu-Hsing Cheng

Journal of Microbiology, Immunology and Infection (Jun 2020)

Lopinavir/ritonavir did not shorten the duration of SARS CoV-2 shedding in patients with mild pneumonia in Taiwan

Chien-Yu Cheng,
Yu-Lin Lee,
Cheng-Pin Chen,
Yi-Chun Lin,
Chun-Eng Liu,
Chia-Hung Liao,
Shu-Hsing Cheng

Affiliations

Chien-Yu Cheng: Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; School of Public Health, National Yang-Ming University, Taipei, Taiwan
Yu-Lin Lee: Department of Internal Medicine, Changhua Christian Hospital, Taiwan
Cheng-Pin Chen: Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
Yi-Chun Lin: Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
Chun-Eng Liu: Department of Internal Medicine, Changhua Christian Hospital, Taiwan
Chia-Hung Liao: Department of Internal Medicine, Nantou Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
Shu-Hsing Cheng: Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; School of Public Health, Taipei Medical University, Taipei, Taiwan; Corresponding author. Division of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan. Fax: +886 3 3789127.

Journal volume & issue: Vol. 53, no. 3
pp. 488 – 492

Abstract

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An increase of Ct values was 0.9 per day in 2 cases of COVID-19 treated with lopinavir/ritonavir (LPV/r), an increase was 1.0 per day in 3 cases without LPV/r through illness day 1–10, indicating that LPV/r did not shorten the duration of SARS CoV-2 shedding.

Published in Journal of Microbiology, Immunology and Infection

ISSN: 1684-1182 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Science: Microbiology
Website: https://www.sciencedirect.com/journal/journal-of-microbiology-immunology-and-infection

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