Multiple eruptive myxoid dermatofibromas

Abstract

Multiple eruptive dermatofibromas are a rare presentation of dermatofibroma and have been associated with altered immunity. A rare case of multiple eruptive myxoid dermatofibromas (MEMDFs), characterized by marked stromal mucin deposition, is reported herein; additionally, an in-depth discussion on the implication of altered immunity is presented. Because MEMDFs can be an initial manifestation of systemic lupus erythematosus, it is necessary for dermatologists to perform a skin biopsy for pathological diagnosis and a comprehensive survey for autoimmunity, infectious diseases, especially human immunodeficiency virus infection, hematologic diseases, and malignancies, or other immunodeficiency conditions when the patient is diagnosed with MEMDFs.

Keywords

• multiple eruptive dermatofibromas
• myxoid dermatofibroma
• systemic lupus erythematosus