Minocycline in acne system therapy

Abstract

Systemic antibiotics in combination with topical retinoids and benzoyl peroxide are first-line drugs for the treatment of moderate to severe acne. The systemic antibiotic Minocycline has a wide spectrum of action against gram + and gram-organisms, including strains resistant to penicillins and cephalosporins. A pronounced bacteriostatic effect is achieved by a high level of lipophilicity, rapid penetration through the lipid layer of bacteria and intensive accumulation in the sebaceous glands. Minolexin is a highly effective and safe medication for the treatment of moderate to severe acne and can be recommended for practical use in outpatient practice.

Keywords

• vulgar acne
• pathogenesis
• antibacterial therapy
• minocicline
• acne