OTO Open (Jun 2021)

Treatment Choices in Managing Bethesda III and IV Thyroid Nodules: A Canadian Multi-institutional Study

  • Victoria Kuta MD,
  • David Forner MD, MSc,
  • Jason Azzi MD,
  • Dennis Curry MD, MSc,
  • Christopher W. Noel MD,
  • Kelti Munroe MD,
  • Martin Bullock MD, FRCSC,
  • Ted McDonald PhD,
  • S. Mark Taylor MD, FRCSC,
  • Matthew H. Rigby MD, MPH, FRCSC,
  • Jonathan Trites MD, FRCSC,
  • Stephanie Johnson-Obaseki MD, MPH, FRCSC,
  • Martin J. Corsten MD, FRCSC

DOI
https://doi.org/10.1177/2473974X211015937
Journal volume & issue
Vol. 5

Abstract

Read online

Objective Patient-centered decision making is increasingly identified as a desirable component of medical care. To manage indeterminate thyroid nodules, patients are offered the options of surveillance, diagnostic hemithyroidectomy, or molecular testing. Our objective was to identify factors associated with decision making in this population. Study Design This is a retrospective cross-sectional study of patients with Bethesda III and IV thyroid nodules. Setting Multi-institutional. Methods Factors of interest included age, sex, socioeconomic status (SES), nodule size, institution, attending surgeon, surgeon payment model, and hospital type. Our outcome of interest was the initial management decision made by patients. Results A total of 956 patients were included. The majority of patients had Bethesda III nodules (n = 738, 77%). A total of 538 (56%) patients chose surgery, 413 (43%) chose surveillance, and 5 (1%) chose molecular testing. There was a significant variation in management decision based on attending surgeon (proportion of patients choosing surgery: 15%-83%; P ≤.0001). Fee-for-service surgeon payment models (odds ratio [OR], 1.657; 95% CI, 1.263-2.175; P < .001) and community hospital settings (OR, 1.529; 95% CI, 1.145-2.042; P < .001) were associated with the decision for surgery. Larger nodule size, younger patients, and Bethesda IV nodules were also associated with surgery. Conclusion While it seems appropriate that larger nodules, younger age, and higher Bethesda class were associated with decision for surgery, we also identified attending surgeon, surgeon payment model, and hospital type as important factors. Given this, standardizing management discussions may improve patient-centered shared decision making.