Communications Biology (Sep 2021)

DEVOLUTION—A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data

  • Natalie Andersson,
  • Subhayan Chattopadhyay,
  • Anders Valind,
  • Jenny Karlsson,
  • David Gisselsson

DOI
https://doi.org/10.1038/s42003-021-02637-6
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 14

Abstract

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Natalie Andersson et al. present DEVOLUTION, an algorithm and tool that allows researchers to reconstruct tumor clonal lineages from copy number and/or sequencing data. They validate this method on a diverse cohort of pediatric cancers, demonstrating its potential applications for cancer research.