1393 Discovery of PLX-4107, a selective IKZF2 molecular glue degrader, that modulates suppressive regulatory T cells and demonstrates anti-tumor activity

• Xiaoming Li,
• Simon Bailey,
• Yujun Huang,
• Pengyu Yang,
• Greg Parker,
• Peggy A Thompson,
• Susan Song,
• Linette Yang,
• Alejandro Dearie,
• Stephen Chien,
• Mary E Spalding,
• Sean Choi,
• Gabrielle Blanco,
• Elizabeth Daniele,
• Julia Toth

Affiliations

Xiaoming Li

University of South Carolina, Arnold School of Public Health, Columbia, South Carolina, USA

Simon Bailey

Centre for Health Services Studies, University of Kent, Canterbury, UK

Yujun Huang

Plexium, San Diego, CA, USA

Pengyu Yang

Plexium, San Diego, CA, USA

Greg Parker

Plexium, San Diego, CA, USA

Peggy A Thompson

Plexium, San Diego, CA, USA

Susan Song

Plexium, San Diego, CA, USA

Linette Yang

Plexium, San Diego, CA, USA

Alejandro Dearie

Plexium, San Diego, CA, USA

Stephen Chien

Plexium, San Diego, CA, USA

Mary E Spalding

Plexium, San Diego, CA, USA

Sean Choi

Plexium, San Diego, CA, USA

Gabrielle Blanco

Plexium, San Diego, CA, USA

Elizabeth Daniele

Plexium, San Diego, CA, USA

Julia Toth

Plexium, San Diego, CA, USA