EFFECT OF N-BUTYL-CYANOACRYLATE TISSUE ADHESIVE ON CANINE CORNEAL ULCERS

Abstract

The study was conducted in six dogs with corneal ulcer of varying degree presented to University Veterinary Hospital, Kokkalai and Mannuthy. All dogs had undergone, complete clinical haematological and biochemical examination. Detailed ophthalmic examination was carried out to assess type and extent of corneal ulcer and integrity of cornea. All dogs were advised topical antibiotic as initial treatment modality. Five days later corneal ulcer was sealed with N-butyl-cyanoacrylate tissue adhesive under general anaesthesia and additional support by temporary tarsorrhaphy. Post-operatively all dogs were on Elizabethan collar and continued with topical instillation of antibiotic for few more days. Cornea was graded further for clarity, vascularization, oedema and pigmentation on day 5, 15 and 30. The application of N-butyl-cyanoacrylate was effective for the treatment of corneal ulcers and the dogs regained visual function with improved clarity and minimal complications.

Keywords

• n-butyl-cyanoacrylate
• corneal ulcer
• dogs
• corneal clarity