Nature Communications (Mar 2020)
Complexation-induced resolution enhancement of 3D-printed hydrogel constructs
- Jiaxing Gong,
- Carl C. L. Schuurmans,
- Anne Metje van Genderen,
- Xia Cao,
- Wanlu Li,
- Feng Cheng,
- Jacqueline Jialu He,
- Arturo López,
- Valentin Huerta,
- Jennifer Manríquez,
- Ruiquan Li,
- Hongbin Li,
- Clément Delavaux,
- Shikha Sebastian,
- Pamela E. Capendale,
- Huiming Wang,
- Jingwei Xie,
- Mengfei Yu,
- Rosalinde Masereeuw,
- Tina Vermonden,
- Yu Shrike Zhang
Affiliations
- Jiaxing Gong
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Carl C. L. Schuurmans
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Anne Metje van Genderen
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Xia Cao
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Wanlu Li
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Feng Cheng
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Jacqueline Jialu He
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Arturo López
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Valentin Huerta
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Jennifer Manríquez
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Ruiquan Li
- Department of Surgery-Transplant and Holland Regenerative Medicine Program, University of Nebraska Medical Center
- Hongbin Li
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Clément Delavaux
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Shikha Sebastian
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Pamela E. Capendale
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Huiming Wang
- The Affiliated Stomatology Hospital, Zhejiang University School of Medicine
- Jingwei Xie
- Department of Surgery-Transplant and Holland Regenerative Medicine Program, University of Nebraska Medical Center
- Mengfei Yu
- The Affiliated Stomatology Hospital, Zhejiang University School of Medicine
- Rosalinde Masereeuw
- Department of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University
- Tina Vermonden
- Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Science for Life, Utrecht University
- Yu Shrike Zhang
- Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- DOI
- https://doi.org/10.1038/s41467-020-14997-4
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Three-dimensional (3D) hydrogel printing enables production of volumetric architectures but achieving good resolutions for miniaturized features remains challenging. Here the authors demonstrate shrinking of a printed structure by immersing a 3D-printed patterned hydrogel consisting of a hydrophilic polyionic polymer network in a solution of polyions of the opposite net charge.
