Разработка и регистрация лекарственных средств (Nov 2022)

Lycium: Prospects of Application in Pharmacy of Plant Raw Materials Containing Alkaloids, Flavonoids, Polysaccharides and Other Biologically Active Substances of the <i>Solanaceae</i> Family Plants (Review)

  • B. Tupa,
  • O. G. Potanina,
  • E. V. Uspenskaya

DOI
https://doi.org/10.33380/2305-2066-2022-11-4-28-39
Journal volume & issue
Vol. 11, no. 4
pp. 28 – 39

Abstract

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Introduction. The review is dedicated to the scientific analysis of the composition, properties and features of the biological effects on the man's organism of the Lycium Fruit as a prospective plant raw material for the production of innovative drugs.Text. The most important aspects related to plant raw materials of various types of Lycium are considered, such as, the worldwide prevalence of plants and the unification of raw materials numerous synonymous names, the generalization of pharmacopoeia data, the qualitative and quantitative composition of Lycium components, their structural features, biological effects on vital body systems. The review also presents the problem of the absence of general pharmacopoeia monographs on Lycium raw materials in Russia, despite the cultivation of Lyceum ruthenicum M. plants in Russia. This fact opens up significant opportunities to develop the Russian regulatory document for Lycium, as a promising pharmaceutical raw material.Conclusion. The obtained results demonstrate the potential of introducing into pharmacy a new type of pharmaceutical raw material and a new finished products based on them, as well as predicting the biological activity of the substances of Lycium fruit and mechanisms of alkaloids, flavonoids, polysaccharides and Lycium carotenoids action.

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