mBio (Feb 2021)

Histone Modifications in Papillomavirus Virion Minichromosomes

  • Samuel S. Porter,
  • Jennifer C. Liddle,
  • Kristen Browne,
  • Diana V. Pastrana,
  • Benjamin A. Garcia,
  • Christopher B. Buck,
  • Matthew D. Weitzman,
  • Alison A. McBride

DOI
https://doi.org/10.1128/mBio.03274-20
Journal volume & issue
Vol. 12, no. 1

Abstract

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A relatively unique feature of papillomaviruses is that the viral genome is associated with host histones inside the virion. However, little is known about the nature of the epigenome within papillomavirions or its biological relevance to the infectious viral cycle.