Hesperidin as a natural Radio-Protector
Journal of Fasa University of Medical Sciences. 2016;5(4):449-459
Journal Title: Journal of Fasa University of Medical Sciences
ISSN: 2228-5105 (Print); 2228-7329 (Online)
Publisher: Fasa University of Medical Sciences
Society/Institution: Fasa University of Medical Sciences
LCC Subject Category: Medicine: Medicine (General)
Country of publisher: Iran, Islamic Republic of
Language of fulltext: Persian
Full-text formats available: PDF
Department of Radiology, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Gholamhassan Haddadi ( Department of Medical Physics, Fasa University of Medical Sciences, Fasa, Iran. )
Reza Fardid ( Department of Radiology, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. )
Abstract | Full Text
Despite widespread usage of ionizing radiation in medical diagnosis and treatment methods, development of radio-protective agents is important in modulating normal tissue damages. The inherent toxicity of synthetic compounds and the confirmation of low toxicity of natural compound in accordance with long – term usage of medicine have led many researchers to investigate the radio-protective abilities of natural compounds. Hesperidin (HES) is a flavanone glycoside, belonging to the flavonoid family found in human diet abundantly and noted for its many beneficial effects. However, hesperidin has fewer protective effects than synthetic compounds and less toxicity and possibility of oral administration. That is why it can be offered as a suitable radio-protector in radiotherapy patients, radiation workers, astronauts, and the public.