Romanian Journal of Medical and Dental Education (Apr 2021)

THE IMPACT OF SMOCKING ON THE SALIVARY LEVELS OF RANKL AND OPG IN PACIENTS WITH GENERALIZED, STAGE III, GRADE B, PERIODONTITIS

  • Alexandra-Cornelia Teodorescu,
  • Ioana-Andreea Sioustis,
  • Cristina-Gena Dascalu,
  • Silvia Teslaru,
  • Irina-Georgeta Sufaru,
  • Diana-Cristala Nitescu-Kappenberg,
  • Maria-Alexandra Martu,
  • Ionut Luchian,
  • Liliana Pasarin,
  • Sorina-Mihaela Solomon,
  • Silvia Martu

Journal volume & issue
Vol. 10, no. 2
pp. 22 – 28

Abstract

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The aim of this study was to evaluate the influence of smoking on salivary RANKL and OPG levels in patients with generalized, stage III, grade B periodontitis. Material and methods: The salivary concentrations of RANKL and OPG were determined for 18 patients, aged between 23 and 50 years old, of which 8 were smokers, all presenting with a form of generalized, stage III, grade B periodontitis. Results: smokers had higher salivary levels of RANKL (p=0,0009) and a higher RANKL/OPG ratio (p=0,019), compared to non-smokers. OPG salivary levels did not differ much between smokers and non-smokers. Conclusions: Smoking has a higher impact on RANKL than on OPG salivary levels, for patients with generalized, stage III, grade B, periodontitis.

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