Nature Communications (Apr 2022)

A single-cell nanocoating of probiotics for enhanced amelioration of antibiotic-associated diarrhea

  • Jiezhou Pan,
  • Guidong Gong,
  • Qin Wang,
  • Jiaojiao Shang,
  • Yunxiang He,
  • Chelsea Catania,
  • Dan Birnbaum,
  • Yifei Li,
  • Zhijun Jia,
  • Yaoyao Zhang,
  • Neel S. Joshi,
  • Junling Guo

DOI
https://doi.org/10.1038/s41467-022-29672-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

Read online

Here, the authors develop a polyphenol-based single-cell coating that forms a nanoarmor on the surface of probiotics, showing that protects from a wide range of antibiotics and enhances probiotic action against antibiotic-mediated diarrhea.