Fayixue Zazhi (Oct 2024)

The Impact of STR Mutations on Kinship Identification

  • LIU Jing,
  • WANG Zheng,
  • HOU Yi-ping,
  • LIAO Lin-chuan

DOI
https://doi.org/10.12116/j.issn.1004-5619.2024.541008
Journal volume & issue
Vol. 40, no. 5
pp. 484 – 491

Abstract

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Kinship identification is an important field of forensic genetics research, which can be widely applied in inheritance disputes, criminal investigations, and the identification of victims in major disaster cases. At present, capillary electrophoresis-based STR analysis is still the main method for kinship identification, but the impact of STR mutations on kinship identification needs further exploration. This paper reviews the theoretical basis and research status at home and abroad of kinship identification. The challenge of STR mutation impact on kinship identification is prospected, and possible solutions are discussed in order to obtain a regular understanding of the impact of STR mutation on kinship identification and improve the accuracy of kinship analysis.

Keywords