Nature Communications (Jan 2021)

Benchmarking joint multi-omics dimensionality reduction approaches for the study of cancer

  • Laura Cantini,
  • Pooya Zakeri,
  • Celine Hernandez,
  • Aurelien Naldi,
  • Denis Thieffry,
  • Elisabeth Remy,
  • Anaïs Baudot

DOI
https://doi.org/10.1038/s41467-020-20430-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Advances in omics technology have resulted in the generation of multi-view data for cancer samples. Here, the authors compare dimensionality reduction techniques using simulated and TCGA data and identify the features of the methods with superior performance.