Lymphocyte-rich classical hodgkin's lymphoma involving submandibular salivary gland: A case report

Abstract

Hodgkin's lymphoma (HL) is a malignant disease of the lymphoid tissue originating from the germinal center and postgerminal center B-cells comprising 10% of all lymphomas and 0.6% among all cancers. Here, we report a case of a 22-year-old male with a chief complaint of painless swelling in the right submandibular region for the past 6 months with no contributory medical history. Correlating the history and clinical examination, a clinical diagnosis of benign sialadenoma was made. Benign sialadenoma was confirmed on radiographic investigations such as ultrasonography and magnetic resonance imaging. Furthermore, excisional biopsy and immunohistochemistry performed revealed a case of classical HL (lymphocyte-rich type). The positron-emission tomography–computed tomography revealed metastasis to the inguinal and cervical lymph nodes.

Keywords

• classical hodgkin's lymphoma
• immunohistochemistry
• magnetic resonance imaging
• positron emission tomography–computed tomography
• ultrasonography