Nature Communications (Nov 2021)

Arabidopsis P4 ATPase-mediated cell detoxification confers resistance to Fusarium graminearum and Verticillium dahliae

  • Fanlong Wang,
  • Xianbi Li,
  • Yujie Li,
  • Jing Han,
  • Yang Chen,
  • Jianyan Zeng,
  • Mei Su,
  • Jingxin Zhuo,
  • Hui Ren,
  • Haoru Liu,
  • Lei Hou,
  • Yanhua Fan,
  • Xingying Yan,
  • Shuiqing Song,
  • Juan Zhao,
  • Dan Jin,
  • Mi Zhang,
  • Yan Pei

DOI
https://doi.org/10.1038/s41467-021-26727-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 16

Abstract

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Toxic metabolites produced by phytopathogens can subvert host immunity. Here the authors show that the Arabidopsis P4-ATPases, AtALA1 and AtALA7 mediate mycotoxin detoxification by promoting vesicle transport and their subsequent sequestration and degradation in vacuoles.