Progress on the role of N-acetyltransferase 10 in tumor development

GU Zhongjia, LAI Siying, CHEN Dunjin, DU Lili

doi:10.16352/j.issn.1001-6325.2024.11.1589

Jichu yixue yu linchuang (Nov 2024)

Progress on the role of N-acetyltransferase 10 in tumor development

GU Zhongjia, LAI Siying, CHEN Dunjin, DU Lili

Affiliations

GU Zhongjia, LAI Siying, CHEN Dunjin, DU Lili: Guangzhou Institute of Obstetrics and Gynecology,Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine,the Third Affiliated Hospital of Guangzhou Medical University,Guangzhou 510000,China

DOI: https://doi.org/10.16352/j.issn.1001-6325.2024.11.1589
Journal volume & issue: Vol. 44, no. 11
pp. 1589 – 1593

Abstract

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N-acetyltransferase10(NAT10) is a protein widely expressed in a variety of tissues and cells. The high expression of NAT10 is closely related to tumor invasion, metastasis and drug resistance. The mechanism of NAT10 promoting tumor genesis and development involves the regulation of cell cycle, mRNA stability, translation efficiency and related pathways due to the changes in the expression or location of NAT10, thus affecting the occurrence, development and prognosis of tumors.

n-acetyltransferase10|n4-acetylcytidine|tumor

Published in Jichu yixue yu linchuang

ISSN: 1001-6325 (Print)
Publisher: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
Country of publisher: China
LCC subjects: Medicine
Website: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/1001-6325/home.shtml

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