BMC Nephrology (Oct 2004)

Atherosclerotic renal artery stenosis: one year outcome of total and separate kidney function following stenting

  • Ronga Giuseppe,
  • Nofroni Italo,
  • Lavini Raffaella,
  • Catalano Carlo,
  • Moscaritolo Eleonora,
  • Coen Giorgio,
  • Sardella Daniela,
  • Zaccaria Alvaro,
  • Cianci Rosario

DOI
https://doi.org/10.1186/1471-2369-5-15
Journal volume & issue
Vol. 5, no. 1
p. 15

Abstract

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Abstract Background Renal artery stenosis (RAS) is a known cause of hypertension and ischemic nephropathy. Stenting of the artery is a valid approach, in spite of cases of unexpected adverse evolution of renal function. Methods In this study, 27 patients with unilateral RAS were subjected to stenting and followed for a period of one year, while 19 patients were observed while on medical treatment only. The group of 27 patients, 67.33 ± 6.8 years of age, creatinine of 2.15 ± 0.9 mg/dl, following stenting, were followed at intervals with biochemical tests, renal scintigraphy and doppler ultrasonography. The control group (70.0 ± 6.1 years, creatinine 1.99 ± 0.7 mg/dl) was also followed for one year. Result One year after stenting mean creatinine clearance (Ccr) increased from 36.07 ± 17.2 to 40.4 ± 21.6 ml/min (NS). Arterial BP, decreased after 1,3,6, and 12 months (p Conclusions Stenting of RAS due to atherosclerosis is followed by stabilization or improvement of Ccr, mainly at the stented kidney, while contralateral renal function showed a decrease.