Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
Muhammad Issa Khan,
Maria Maqsood,
Raakia Anam Saeed,
Amna Alam,
Amna Sahar,
Marek Kieliszek,
Antoni Miecznikowski,
Hafiz Shehzad Muzammil,
Rana Muhammad Aadil
Affiliations
Muhammad Issa Khan
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Maria Maqsood
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Raakia Anam Saeed
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Amna Alam
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Amna Sahar
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Marek Kieliszek
Department of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences—SGGW, Nowoursynowska 159 C, 02-776 Warsaw, Poland
Antoni Miecznikowski
Department of Fermentation Technology, Prof. Waclaw Dabrowski Institute of Agricultural and Food Biotechnology—State Research Institute, Rakowiecka 36, 02-532 Warsaw, Poland
Hafiz Shehzad Muzammil
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Rana Muhammad Aadil
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan
Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.
