New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi
Ahmed Elkhateeb,
Ahmed A. El-Beih,
Amira M. Gamal-Eldeen,
Montaser A. Alhammady,
Shinji Ohta,
Paul W. Paré,
Mohamed-Elamir F. Hegazy
Affiliations
Ahmed Elkhateeb
Phytochemistry and Plant Systematic Department, National Research Centre, El-Tahrir St., Dokki, Giza 12311, Egypt
Ahmed A. El-Beih
Department of Chemistry of Natural & Microbial Products and Center of Excellence Advanced Sciences, National Research Centre, El-Tahrir Street, Dokki, Giza 12311, Egypt
Amira M. Gamal-Eldeen
Cancer Biology Lab, Center of Excellence for Advanced Sciences & Biochemistry Department, National Research Center, Dokki, Cairo 12311, Egypt
Montaser A. Alhammady
National Institute of Oceanography and Fisheries, Red Sea Branch, Hurghada 84511, Egypt
Shinji Ohta
Graduate School of Biosphere Science, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima 739-852, Japan
Paul W. Paré
Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA
Mohamed-Elamir F. Hegazy
Chemistry of Medicinal Plants Department and Center of Excellence Advanced Sciences, National Research Centre, El-Tahrir Street, Dokki, Giza 12311, Egypt
Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1–3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines.
