Nature Communications (Jul 2019)

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

  • Mark R. Viant,
  • Timothy M. D. Ebbels,
  • Richard D. Beger,
  • Drew R. Ekman,
  • David J. T. Epps,
  • Hennicke Kamp,
  • Pim E. G. Leonards,
  • George D. Loizou,
  • James I. MacRae,
  • Bennard van Ravenzwaay,
  • Philippe Rocca-Serra,
  • Reza M. Salek,
  • Tilmann Walk,
  • Ralf J. M. Weber

DOI
https://doi.org/10.1038/s41467-019-10900-y
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Lack of best practice guidelines currently limits the application of metabolomics in the regulatory sciences. Here, the MEtabolomics standaRds Initiative in Toxicology (MERIT) proposes methods and reporting standards for several important applications of metabolomics in regulatory toxicology.