Clinical study on epilepsy secondary to fungal meningitis

Abstract

The clinical manifestations, cerebrospinal fluid (CSF), imaging and EEG characteristics of 10 patients with epilepsy secondary to fungal meningitis were retrospectively analyzed, so as to improve the diagnosis and treatment of fungal meningitis. The results suggest that patients with fungal meningitis involving the cortex were sensitive to secondary epilepsy; imaging examinations showing frontotemporal lesions and EEG showing moderate-to-severe abnormalities were sensitive to secondary epilepsy. Whether the increasing of endotoxin and (1-3)-β-D-dextran in CSF of patients with fungal meningitis is associated with secondary epilepsy needs further research. DOI: 10.3969/j.issn.1672-6731.2015.02.015

Keywords

• Meningitis, fungal
• Epilepsy
• Cerebrospinal fluid
• Magnetic resonance imaging
• Electroencephalography