Arquivos Brasileiros de Cardiologia (Sep 2010)
Síndrome metabólica e menopausa: estudo transversal em ambulatório de ginecologia Síndrome metabólico y menopausia: estudio transversal en ambulatorio de ginecología Metabolic syndrome and menopause: cross-sectional study in gynecology clinic
Abstract
FUNDAMENTO: No Brasil, são escassos os estudos sobre síndrome metabólica na população geral, mais raros são os que a correlacionam ao climatério. OBJETIVO: Determinar a prevalência da síndrome metabólica e seus componentes em mulheres climatéricas. MÉTODOS: Estudo transversal com 323 mulheres climatéricas, divididas em dois grupos: pré e pós-menopausadas. Foram avaliadas para presença de síndrome metabólica, segundo os critérios do National Cholesterol Education Program's (NCEP) e da International Diabetes Federation (IDF). Foi verificada a associação entre as variáveis estudadas e a síndrome metabólica por meio de análise uni e multivariada. Um p-valor FUNDAMENTO: En Brasil, son raros los estudios sobre síndrome metabólico en la población general, más raros son los que la correlacionan al climaterio. OBJETIVO: Determinar la prevalencia del síndrome metabólico y sus componentes en mujeres climatéricas. MÉTODOS: Estudio transversal con 323 mujeres climatéricas, divididas en dos grupos: pre y posmenopáusicas. Se evaluaron para presencia de síndrome metabólico, según los criterios del NCEP y de la IDF. Se verificó la asociación entre las variables estudiadas y el síndrome metabólico por medio de análisis uni e multivariado. Un p-valor BACKGROUND: In Brazil, there are few studies of the metabolic syndrome in the general population, and even fewer studies that establish a correlation between metabolic syndrome and climacteric. OBJECTIVE: To determine the prevalence of metabolic syndrome and its components among climacteric women. METHODS: Cross-sectional study with 323 climacteric women, divided into two groups: pre and post-menopausal. They were examined for the presence of metabolic syndrome, according to the criteria of National Cholesterol Education Program's (NCEP) and International Diabetes Federation (IDF). It was possible to notice the association between the variables under study and the metabolic syndrome by conducting a univariate analysis and a multivariate analysis. A p-value < 0.05 was considered statistically significant. RESULTS: The prevalence of metabolic syndrome during the climacteric was 34.7% (NCEP) and 49.8% (IDF). The most frequent components of the metabolic syndrome were low HDL-cholesterol, hypertension, abdominal obesity, hypertriglyceridemia and diabetes in both criteria. The multivariate analysis showed that age was the most important risk factor for the development of metabolic syndrome (p < 0.001), which was present in 44.4% (NCEP) and 61.5% (IDF) of postmenopausal women compared to 24% (NCEP) and 37% (IDF) of premenopausal women. CONCLUSION: The prevalence of metabolic syndrome was higher in postmenopausal women than in premenopausal women. The main risk factor for the increase in this prevalence was age. Menopause, when it is analyzed alone, did not constitute a risk factor for metabolic syndrome.
